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Cystic Fibrosis Treatment in Iran Details

What is Cystic Fibrosis?

A chronic disease affecting different organs that include intestines, liver, pancreas, and lungs are known as cystic fibrosis (CF).

The salt of the body is disrupted that leaves very little water and salt on the outside of the cells.

This results in thinning of the mucus layer that keeps the lungs free of germs to become sticky and thick.

This mucus causes clogging of the lungs and is even difficult to cough out, which ultimately result in infections and damaged lungs.

The digestion process also gets affected due to cystic fibrosis mucus, and it also stops the natural enzymes that help in absorbing food.

Cystic Fibrosis Treatment in Iran

Causes of Cystic Fibrosis

The mutation in a gene known as the cystic fibrosis transmembrane conductance regulator (CFTR) is responsible for causing cystic fibrosis.

CFTR is responsible for creating digestive juices, sweat, and mucus.

When the protein does not work well, it results in salty and very sticky sweat in those people who are suffering from cystic fibrosis. 

Symptoms of Cystic Fibrosis

Some of the common symptoms include the followings:

  • Nasal polyps (fleshy and small growths in the nose)
  • Salty skin
  • Wheezing
  • Frequent bulky and greasy stools or trouble with defecation
  • Recurrent infections that include bronchitis and pneumonia
  • Shortness of breath
  • Constant coughing, usually with extra mucus or phlegm
  • Little weight gain and poor growth even when there is a good appetite

CF is also connected with certain symptomatic conditions and diseases that include problems with a gastrointestinal system like diabetes, poor growth, malabsorption, infertility, clubbing of toes and fingers and blockages. 

Cystic Fibrosis Treatment in Iran

Diagnosis of Cystic Fibrosis

Physical examination, family history, and symptoms of the patient are analyzed while diagnosing cystic fibrosis.

Some patients can even be diagnosed with the help of newborn screening.

The first standardized test for diagnosing cystic fibrosis is the sweat test.

This test examines the quantity of salt present in the perspiration of a patient.

Immunoreactive trypsinogen test, which is a type of blood test, is required for diagnosing CF in children as they are unable to produce enough sweat.

The presence of cystic fibrosis genes is confirmed by performing a genetic test.

Cystic Fibrosis Treatment in Iran

Treatment for Cystic Fibrosis

Cystic fibrosis has no specific treatment.

The quality of life can be improved by providing specialized medical care, proper nutrition, and aggressive drug therapies and treatments.

The treatment provided also depends upon the symptoms and severity of the disease due to specific gene mutation.

Antibiotics can be taken for suppressing the development of infections.   

The aim of cystic fibrosis treatment is to clear the mucus from the airways.

Certain kinds of vibrations are used for loosening the mucus in the lungs to cough out this mucus.

Certain medications like antibiotics, bronchodilators, mucus thinners, and anti-inflammatories are used that helps in breathing and for assisting in the expulsion of mucus.

To block pancreatic enzymes from entering the intestines, pancreatic enzyme supplements are used that are taken before the meals.

These pancreatic enzyme supplements help in digesting the food properly, and it also provides for proper nutrition.

Double lung transplantation is also sometimes recommended when the function of the lung is very low.

Cystic Fibrosis Treatment

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